The team is experienced in investigating the mechanism of natural product biosynthesis, and applying combinatorial biosynthesis and enzyme technology for the production of natural products including polyketides (PKS), non-ribosomal peptides (NRPS), terpenoids and their derivatives from hybridization, post-translation and glycosylation.
One pathway is to develop enzyme toolboxes to catalyze the transformation of chemicals in vitro and the other is to construct multi-enzyme systems to make chemicals via cell factory through integration of metabolic engineering and strain engineering. Our collaborators include a number of institutes and universities both domestic and overseas.